- Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson’s Disease
- Refining Cough Skill Training in Parkinson’s Disease and Dysphagia
- Rehabilitation of Airway Protection in Parkinson’s Disease
- Adipose-derived Stromal Vascular Fraction Cells to Treat Parkinson
- Precise Transplantation of Human Amniotic Epithelial Stem Cells Into Lateral Ventricle for Parkinson’s Disease.
- Biomarker Validation Following Sargramostim Treatment in Parkinson’s Disease
- A Study to Evaluate Safety and Efficacy of KM-819 in Healthy Adults and Participants With Parkinson’s Disease
- Methylphenidate for Apathy in Veterans With Parkinson’s Disease
- A Study of Suvecaltamide in Adults With Moderate to Severe Residual Tremor in Parkinson’s Disease
- Altropane Dose for Imaging Patients With Suspected Parkinson’s Disease
- Relative Bioavailability and Food Effect Study of CVN424
- A Trial to Determine the Safety and Tolerability of Transplanted Stem Cell Derived Dopamine Neurons to the Brains of Individuals With Parkinson’s Disease
- UB-312 in Patients With Synucleinopathies
- Safety of CERE-120 (AAV2-NTN) in Subjects With Idiopathic Parkinson’s Disease
- Double-Blind, Multicenter, Sham Surgery Controlled Study of CERE-120 in Subjects With Idiopathic Parkinson’s Disease
- Efficacy and Safety of Rasagiline in Prodromal Parkinson’s Disease
- Multiple-dose Trial to Determine the Clinical Bioequivalence Between Tavapadon Tablets in Participants With Parkinson’s Disease
- Antidepressants Trial in Parkinson’s Disease
- Pyridostigmine for the Treatment of Constipation in Parkinson Disease
- A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson’s Participants
- Cognitive Training in Parkinson’s Disease
- Intermittent Oral Administration vs. Semi-continuous Intra-oral Administration of Levodopa/Carbidopa in Fluctuating Parkinsonian Patients
- Study to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Inducer Carbamazepine on Tavapadon Pharmacokinetics in Healthy Adult Participants
- Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson’s Disease
- Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson’s Disease
- Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson’s Disease (PD)
- Clinical Efficacy and Safety Evaluation of Nicergoline in Patients With Neurological Dysphagia.
- An Extension Study to Evaluate the Long-Term Efficacy, Safety and Tolerability of UCB0599 in Study Participants With Parkinson’s Disease
- AMDX-2011P Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy
- A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)
- A Study to Evaluate the Safety, Tolerability, PK and PD of HNC364 Injectable Suspension
- Open-Label Extension Study of ASTORIA
- Vibrotactile Coordinated Reset for the Treatment of Advanced Parkinson’s Disease
- Intranasal Human FGF-1 for Subjects With Parkinson’s Disease
- Effect of Doxycycline in Levodopa Treated Parkinson’s Disease Patients
- Open Label Study for the Use of Transcranial Ultrasound Treatment of Tremor
- Safety, Tolerability, and Pharmacokinetics of Oral FB-101 in Healthy Subjects
- Sustained Release Oral Formulation for Treatment of Parkinson’s Disease
- Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Tributyrin Supplementation
- Assessing Imaging as a Tool in Monitoring and Predicting the Progression of Parkinson Disease
- PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
- Precise Transplantation of hAESCs Into the Ventricle for Parkinson’s Disease.
- A Pharmacodynamics and Safety Study of DSP-9632P in Patients With Levodopa-Induced Dyskinesia in Parkinson’s Disease
- A Randomized, Double-Blind, Placebo-Controlled Trial of IkT-148009 in Untreated Parkinson’s Disease
- A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson’s Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale
- A Study to Assess the PK and Pharmacodynamics of IPX203 in Subjects With Advanced Parkinson’s Disease
- CANadian Adaptive DBS TriAl
- Feasibility and Safety of autoloGous UncondItioneD pEripheral Nerve Tissue Delivery to the Substantia Nigra (GUIDE)
- A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD
- Safety and Efficacy of AVP-923 in the Treatment of Levodopa-induced Dyskinesia in Parkinson’s Disease Patients
- Trial of Ondansetron as a Parkinson’s HAllucinations Treatment
- A Study to Assess the Safety of BIIB122 Tablets and if it Can Slow the Worsening of Early-Stage Parkinson’s Disease in Participants Between the Ages of 30 and 80
- A Study to Evaluate Iloperidone for the Treatment of Parkinson’s Disease Psychosis
- Istradefylline for Parkinson Disease With Cognitive Impairment
- A Study to Evaluate the Effects of SAGE-718 in Participants With Parkinson’s Disease Cognitive Impairment
- Efficacy, Safety and Pharmacokinetic Study of CPL500036 in Patients With Levodopa Induced Dyskinesia
- A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed With Parkinson’s Disease
- Brain Bioenergetics in Parkinson’s Disease and Response to Repeated Oral UDCA Treatment
- Ambroxol as a Disease-modifying Treatment in GBA-PD
- A Clinical Study of Efficacy, Safety, Tolerability and PK of ND0612H in Subjects With Advanced Parkinson’s Disease
- Cannabis Oil for Pain in Parkinson’s Disease
- Proof of Mechanism Study to Evaluate Binding of Alfa-synuclein
- Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson’s Disease
- A Long-term, Phase 3 Study of TVP-1012 (1 mg) in Levodopa Treated Parkinson’s Disease Participants
- A Phase 3, Long-term, Extension Study of TVP-1012 (1 mg) in Early Parkinson’s Disease Participants
- A Phase 2/3 Study of TVP-1012 at 0.5 mg or 1 mg in Levodopa Treated Parkinson’s Disease Participants
- A Phase 3 Study of TVP-1012 (1 mg) in Early Parkinson’s Disease Patients
- A Clinical Study Evaluating Efficacy of Pirepemat on Falls Frequency in Patients With Parkinson’s Disease (PD)
- Mass Balance Recovery and Metabolite Identification of Carbon-14 BIA 28-6156
- Robotic Gait Rehabilitation in Parkinson’s Disease
- Multiple N-of-1 Trials of (Intermittent) Hypoxia Therapy in Parkinson’s Disease
- Effect of Fecal Microbiota Transfer on Progression of Parkinson Disease
- Ketamine for the Treatment of Depression in Parkinson’s Disease
- DBS of the MLR for Gait and Balance Disorders in PD Patients
- Intravenous Plasma Treatment for Parkinson’s Disease
- Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Parkinson’s Disease
- Study to Assess the Safety, Tolerability and Preliminary Efficacy of NLX-112 Versus Placebo in L-dopa-induced Dyskinesia
- Comparative Bioavailability Study of Carbidopa/Levodopa Extended-Release Tablets Under Fasting and Fed Conditions
- Open-label Safety Study of Dipraglurant (ADX48621) in Patients With Parkinson’s Disease Receiving Levodopa-based Therapy
- Spinal Cord sTimulation thEraPy for Parkinson’s Disease Patients With Gait Problems
- Terazosin and Parkinson’s Disease Extension Study
- A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson’s or Alzheimer’s Disease
- Effect of Meditation and Controls and Subjects With Parkinson’s Disease on Brain Activity Measured by fMRI With FDOPA
- A Study to Assess Single and Multiple Doses of IkT-148009 in Healthy Elderly Participants and Parkinson’s Patients
- Study to Assess How ABBV-951 is Absorbed When Administered at Different Subcutaneous Sites of Adult Participants With Parkinson’s Disease
- Evaluating Safety, Tolerability, and Efficacy of Autologous MitoCell Transplantation in Subjects With Idiopathic Parkinson’s Disease
- A 6-month Study to Evaluate Sulforaphane Effects in PD Patients
- NE3107 Activity and Safety in Patients With Parkinson’s Disease Using Levodopa
- Valiloxybate (XW10172 MR) Efficacy and Safety Parkinson’s Disease Study
- A Study of CST-2032 in Subjects With Cognitive Impairment
- A Study of the Efficacy and Safety of Carbidopa-Levodopa Extended-Release Tablets in Patients With Parkinson’s Disease
- Effects of Lingzhi on Disease Progression in Patients With Untreated Early Parkinson’s Disease
- Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease
- Manipulating and Optimising Brain Rhythms for Enhancement of Sleep
- Novelty of Sphingolipids in the Central Nervous System Physiology and Disease: Focusing on the Sphingolipid Hypothesis of Neuroinflammation and Neurodegeneration
- Occupancy of Adenosine A2A Receptors Using the PET Radiotracer [18F]MNI-444
- Hypoxia-Inducible Factor (HIF) in Ischemic Stroke and Neurodegenerative Disease
- Discovery of novel and potent safinamide-based derivatives as highly selective hMAO-B inhibitors for treatment of Parkinson’s disease (PD): Design, synthesis, in vitro, in vivo and in silico biological studies
- Natural products attenuate PI3K/Akt/mTOR signaling pathway: A promising strategy in regulating neurodegeneration
- Potentials of autophagy enhancing natural products in the treatment of Parkinson disease
- Towards adaptive deep brain stimulation: clinical and technical notes on a novel commercial device for chronic brain sensing
- Virtual Screening and Biological Activity Evaluation of New Potent Inhibitors Targeting LRRK2 Kinase Domain
- Phytochemicals targeting oxidative stress, interconnected neuroinflammatory and neuroapoptotic pathways following radiation
- Posterior Subthalamic Area, Pallidothalamic Tract, and Pedunculopontine Nucleus:Deep Brain Stimulation Targets for Parkinson’s Disease and Essential Tremor
- Chinese Herbal Medicine Treatment Based on Subgroup Differentiation as Adjunct Therapy for Parkinson’s Disease: a Pilot add-on, Randomised, Controlled, Pragmatic Clinical Trial
- Are lysosomes potential therapeutic targets for Parkinson’s disease?
- Are lysosomes potential therapeutic targets for Parkinson’s disease?
- Next-Generation Gene Therapy for Parkinson’s Disease Using Engineered Viral Vectors
- The Prion-Like Spreading of Alpha-Synuclein in Parkinson’s Disease: Update on Models and Hypotheses
- Identification of pimavanserin tartrate as a potent Ca2+ -calcineurin-NFAT pathway inhibitor for glioblastoma therapy
- Clinical Trial for Parkinson’s Disease Using Allogeneic HB-adMSCs (Early and Moderate) (PD)
- Dopamine D3 Receptors: From Bench to Bedside
- Current advances in metabolomic studies on non-motor psychiatric manifestations of Parkinson’s disease (Review)
- Neither a Novel Tau Proteinopathy nor an Expansion of a Phenotype: Reappraising Clinicopathology-Based Nosology
- UHPLC-MS-based metabolomics and chemoinformatics study reveals the neuroprotective effect and chemical characteristic in Parkinson’s disease mice after oral administration of Wen-Shen-Yang-Gan decoction
- α-Synuclein Selectively Impairs Motor Sequence Learning and Value Sensitivity: Reversal by the Adenosine A2A Receptor Antagonists
- Modulation of the Interactions Between α-Synuclein and Lipid Membranes by Post-translational Modifications
- 4,4′-Dimethoxychalcone regulates redox homeostasis by targeting riboflavin metabolism in Parkinson’s disease therapy
- Novel case of Parkinson’s disease and schizophrenia: challenges in the management
- Necroptosis: A Novel Pathway in Neuroinflammation
- Emerging therapeutics in Huntington’s Disease
- Functionalized polyanhydride nanoparticles for improved treatment of mitochondrial dysfunction
- Early ParkinSon wIth L-DOPA/DDCI and OpicapoNe (EPSILON Study)
- A technology evaluation of CVT-301 (Inbrija): an inhalable therapy for treatment of Parkinson’s disease
- The role of glutamatergic neurotransmission in the motor and non-motor symptoms in Parkinson’s disease: Clinical cases and a review of the literature
- The iron chelator, PBT434, modulates transcellular iron trafficking in brain microvascular endothelial cells
- Alpha-Synuclein Pathology Coincides With Increased Number of Early Stage Neural Progenitors in the Adult Hippocampus
- A Novel NAD Signaling Mechanism in Axon Degeneration and its Relationship to Innate Immunity
- High Fiber in Parkinson’s Disease
- Safety Evaluation of Intravenous Talineuren (TLN) in Parkinson’s Disease-affected Patients
- SCD inhibition protects from Alpha Synuclein induced neurotoxicity but is toxic to early neuron cultures
- Parkinson Disease-Modification Encompassing Rotenone and 6-Hydroxydopamine Neurotoxicity by the Microtubule-Protecting Drug Candidate SKIP
- Structural binding site comparisons reveal Crizotinib as a novel LRRK2 inhibitor
- Diagnostic Performance of miR-485-3p in Patients with Parkinson’s Disease and its Relationship with Neuroinflammation
- PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway
- Search for safer and potent natural inhibitors of Parkinson’s disease
- Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure
- A Study to Assess the Safety and Efficacy of Levodopa-carbidopa Intestinal Gel (LCIG) for the Treatment of Non-motor Symptoms in Patients With Advanced Parkinson’s Disease
- Therapeutic Potential of a Novel Glucagon-like Peptide-1 Receptor Agonist, NLY01, in Experimental Autoimmune Encephalomyelitis
- OIn vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain
- Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects
- Electrochemical flow injection analysis of the interaction between pyrroloquinoline quinone (PQQ) and alpha-synuclein peptides related to Parkinson’s disease
- MiR-20a-5p Regulates MPP+ -Induced Oxidative Stress and Neuroinflammation in HT22 Cells by Targeting IRF9/NF-κ B Axis
- Caveolin-1, a Novel Player in Cognitive Decline
- ATH434 Reduces α-Synuclein-Related Neurodegeneration in a Murine Model of Multiple System Atrophy
- Small heterodimer partner (SHP) aggravates ER stress in Parkinson’s disease-linked LRRK2 mutant astrocyte by regulating XBP1 SUMOylation
- Near-focus narrow-band imaging classification of villous atrophy in suspected celiac disease: development and international validation
- Novel Drug Delivery System for Curcumin: Implementation to Improve Therapeutic Efficacy against Neurological Disorders
- The tuberomamillary nucleus in neuropsychiatric disorders
- Apomorphine Pump in Early Stage of Parkinson’s Disease (EARLY-PUMP)
- Significance of PD1 Alternative Splicing in Celiac Disease as a Novel Source for Diagnostic and Therapeutic Target
- Neurological and Neurodegenerative Disorders: Novel Concepts and Treatment
- New approaches for developing multi-targeted drug combinations for disease modification of complex brain disorders. Does epilepsy prevention become a realistic goal?
- miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease
- The Footprint of Kynurenine Pathway in Neurodegeneration: Janus-Faced Role in Parkinson’s Disorder and Therapeutic Implications
- PEP-1-GLRX1 Reduces Dopaminergic Neuronal Cell Loss by Modulating MAPK and Apoptosis Signaling in Parkinson’s Disease
- Cytoprotective Mechanisms of DJ-1: Implications in Cardiac Pathophysiology
- Recent Insights into the Interplay of Alpha-Synuclein and Sphingolipid Signaling in Parkinson’s Disease
- Moving towards Integrated and Personalized Care in Parkinson’s Disease: A Framework Proposal for Training Parkinson Nurses
- Neuroprotective Effects of Trehalose and Sodium Butyrate on Preformed Fibrillar Form of alpha-Synuclein-Induced Rat Model of Parkinson’s Disease
- Inhibition of α -Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice
- Celiac Disease: Fallacies and Facts
- Mini review – The role of Glucocerebrosidase and Progranulin as possible targets in the treatment of Parkinson’s disease
- The value of a biopsy in celiac disease follow up: assessment of the small bowel after 6 and 24 months treatment with a gluten free diet
- Multiple allelic associations from genes involved in energy metabolism were identified in celiac disease
- LRRK2-NFATc2 Pathway Associated with Neuroinflammation May Be a Potential Therapeutic Target for Parkinson’s Disease
- Emerging COVID-19 Neurological Manifestations: Present Outlook and Potential Neurological Challenges in COVID-19 Pandemic
- Integrated network analysis identifying potential novel drug candidates and targets for Parkinson’s disease
- Regenerative medicine for neurological diseases-will regenerative neurosurgery deliver?
- Symptoms of gluten ingestion in patients with non-celiac gluten sensitivity: A randomized clinical trial
- A Study of CST-103 Co-administered With CST-107 in Subjects With Parkinson’s Disease Having Freezing of Gait (CLIN-012)
- Induction of specific brain oscillations may restore neural circuits and be used for the treatment of Alzheimer’s disease
- Persisting Villous Atrophy and Adherence in Celiac Disease: What Does the Patient Want? What Should a Clinician Advise?
- Psilocybin Therapy for Depression and Anxiety in Parkinson’s Disease
- Clinical Trial Highlights -Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2021 Update
- Mechanisms of Modulation of Ferroptosis and Its Role in Central Nervous System Diseases
- Immune System and Neuroinflammation in Idiopathic Parkinson’s Disease: Association Analysis of Genetic Variants and miRNAs Interactions
- Matrigel Enhances Differentiation of Human Adipose tissue-derived Stem Cells into Dopaminergic Neuron
- Panintestinal capsule endoscopy in patients with celiac disease
- Brain-derived neurotrophic factor attenuates cognitive impairment and motor deficits in a mouse model of Parkinson’s disease
- Parkinson’s Disease (Early and Moderate)
- Synthesis of SPIO Nanoparticles and the Subsequent Applications in Stem Cell Labeling for Parkinson’s Disease
- Glitazones Activate PGC-1alpha Signaling via PPAR-gamma: A Promising Strategy for Antiparkinsonism Therapeutics
- The Pathogenesis of Parkinson’s Disease: A Complex Interplay Between Astrocytes, Microglia, and T Lymphocytes?
- Natural Phytochemicals as Novel Therapeutic Strategies to Prevent and Treat Parkinson’s Disease: Current Knowledge and Future Perspectives
- Transcranial photobiomodulation in the management of brain disorders
- Impact of the apelin/APJ axis in the pathogenesis of Parkinson’s disease with therapeutic potential
- Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK2-driven Parkinson’s disease
- Mitochondrial Quality Control: Epigenetic Signatures and Therapeutic Strategies
- Promoting Physical Activity Engagement for People With Early-mid Stage Parkinson’s Disease (Engage-PD)
- Atremorine in Parkinson’s disease: From dopaminergic neuroprotection to pharmacogenomics
- Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model
- RNA pull-down confocal nanoscanning (RP-CONA) detects quercetin as pri-miR-7/HuR interaction inhibitor that decreases α-synuclein levels
- Gut microbiota mediates the absorption of FLZ, a new drug for Parkinson’s disease treatment
- Glucocerebrosidase Gene Therapy Induces Alpha-Synuclein Clearance and Neuroprotection of Midbrain Dopaminergic Neurons in Mice and Macaques
- How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer’s Disease and Other Neurodegenerative Disorders
- Clinical Utility of 18 F-APN-1607 Tau PET Imaging in Patients with Progressive Supranuclear Palsy
- Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamine to Treat Levodopa-Induced Dyskinesia
- Graphene Quantum Dots from Carbonized Coffee Bean Wastes for Biomedical Applications
- Application of In silico Methods in the Design of Drugs for Neurodegenerative Diseases
- Connecting the dots between mitochondrial dysfunction and Parkinson’s disorder: focus mitochondria-targeting therapeutic paradigm in mitigating the disease severity
- PPARγ receptors are involved in the effects of cannabidiol on orofacial dyskinesia and cognitive dysfunction induced by typical antipsychotic in mice
- Classification of intestinal T-cell receptor repertoires using machine learning methods can identify patients with coeliac disease regardless of dietary gluten status
- PPMI Tau PET Imaging
- Movement of Prion-Like alpha-Synuclein along the Gut-Brain Axis in Parkinson’s Disease: A Potential Target of Curcumin Treatment
- Flavonoids, the Family of Plant-derived Antioxidants making inroads into Novel Therapeutic Design against IR-induced Oxidative Stress in Parkinson’s Disease
- Novel Pharmacotherapies in Parkinson’s Disease
- Randomised Crossover Trial of DBS of Differential PSA Regions in Parkinson’s Disease and Tremor
- Safety, tolerability, and immune-biomarker profiling for year-long sargramostim treatment of Parkinson’s disease
- Fyn Kinase-Mediated PKCdelta Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson’s Disease
- Neuropeptide Y Y2 and Y5 receptors as potential targets for neuroprotective and antidepressant therapies: Evidence from preclinical studies
- Lactoferrin for Mental Health: Neuro-Redox Regulation and Neuroprotective Effects across the Blood-Brain Barrier with Special Reference to Neuro-COVID-19
- The p75 neurotrophin receptor as a novel intermediate in L-dopa-induced dyskinesia in experimental Parkinson’s disease
- The promise of crowdfunding to finance R&D of novel diagnostics and therapeutics for incurable diseases that are underfunded
- Apomorphine Effects on Pain in Parkinson’s Disease
- Further characterisation of psychosis-like behaviours induced by L-DOPA in the MPTP-lesioned marmoset
- Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson’s disease
- p70S6K on astrocytes protects dopamine neurons from 1-methyl-4-phenylpyridinium neurotoxicity
- Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK2 driven parkinson’s disease
- A Study to Test the Safety, Tolerability, and Pharmacokinetics of UCB0599 in Healthy Study Participants and Patients With Parkinson’s Disease (PD)
- Nitric Oxide as a Target for Phytochemicals in Anti-Neuroinflammatory Prevention Therapy
- Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo
- Identification of peculiar gene expression profile in peripheral blood mononuclear cells (PBMC) of celiac patients on gluten free diet
- The production of a recombinant tandem single chain fragment variable capable of binding prolamins triggering celiac disease
- Clinical intervention using Bifidobacterium strains in celiac disease children reveals novel microbial modulators of TNF-alpha and short-chain fatty acids
- The Transcriptomic Analysis of Circulating Immune Cells in a Celiac Family Unveils Further Insights Into Disease Pathogenesis
- NKp46 is a diagnostic biomarker and may be a therapeutic target in gastrointestinal T-cell lymphoproliferative diseases: a CELAC study
- A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease
- Metabolic Signature of Primary Biliary Cholangitis and Its Comparison with Celiac Disease
- Small Bowel Carcinomas Associated with Immune-Mediated Intestinal Disorders: The Current Knowledge
- Promising tacrine/huperzine A- based dimeric AChE inhibitors for neurodegenerative disorders: from relieving symptoms to modifying diseases through multi-target
- Dual Roles of Microglia in the Basal Ganglia in Parkinson’s Disease
- Recent Developments in New Therapeutic Agents against Alzheimer and Parkinson Diseases: In-Silico Approaches
- Chirality of Novel Bitopic Agonists Determines Unique Pharmacology at the Dopamine D3 Receptor
- Histone Methylation Regulation in Neurodegenerative Disorders
- A Study to Test the Safety, Tolerability, and Blood Levels of UCB0022 in Healthy Participants and Participants With Parkinson’s Disease
- A Clinical Study of KDT-3594 in Japanese Patients With Early Parkinson’s Disease
- Oligonucleotides as therapeutic tools for brain disorders: Focus on major depressive disorder and Parkinson’s disease
- Identification of Two Novel Peptides That Inhibit alpha-Synuclein Toxicity and Aggregation
- Vesicular glutamate transporter modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration
- Neuroprotective effects of disubstituted dithiolethione ACDT against manganese-induced toxicity in SH-SY5Y cells
- Potential Roles of Gut Microbiota and Microbial Metabolites in Parkinson’s Disease
- Dietary nutrition for neurological disease therapy: Current status and future directions
- Study to Investigate the Effect of Hypoestes Rosea Powder in Parkinson’s Disease
- Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson’s Disease Receiving Levodopa-based Therapy
- Gene Therapy in Movement Disorders: A Systematic Review of Ongoing and Completed Clinical Trials
- Pharmacological Inhibition of USP30 activates Tissue-specific Mitophagy
- Novel 1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-indene-4-thiol derivatives as potent selective human monoamine oxidase B inhibitors: design, SAR development, and biological evaluation
- Dl-butylphthalide inhibits rotenone-induced oxidative stress in microglia via regulation of the Keap1/Nrf2/HO-1 signaling pathway
- Genetic Modifiers of Age at Onset for Parkinson’s Disease in Asians: A Genome-Wide Association Study
- The pleiotropic effects of antithrombotic drugs in the metabolic-cardiovascular-neurodegenerative disease continuum: impact beyond reduced clotting
- Genome instability and loss of protein homeostasis: converging paths to neurodegeneration?
- Discovery of New Potent Positive Allosteric Modulators of Dopamine D2 Receptors: Insights into the Bioisosteric Replacement of Proline to 3-Furoic Acid in the Melanostatin Neuropeptide
- Magnetic Targeting of Human Olfactory Mucosa Stem Cells Following Intranasal Administration: a Novel Approach to Parkinson’s Disease Treatment
- New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signaling
- Tele-Rehabilitation with Virtual Reality: A Case Report on the Simultaneous, Remote Training of Two Patients with Parkinson Disease
- Optogenetic delivery of trophic signals in a genetic model of Parkinson’s disease
- Effect of SQJZ Herbal Mixtures on Non-motor Symptoms of Parkinson’s Disease
- Potential of medicinal plants as neuroprotective and therapeutic properties against amyloid-beta-related toxicity, and glutamate-induced excitotoxicity in human neural cells
- Granulocyte-macrophage colony-stimulating factor mRNA and Neuroprotective Immunity in Parkinson’s disease
- Astrocytic Kir6.1 deletion aggravates neurodegeneration in the lipopolysaccharide-induced mouse model of Parkinson’s disease via astrocyte-neuron cross talk through complement C3-C3R signaling
- An Exploratory Study of XP21279 (With Lodosyn®) and Sinemet® in Parkinson’s Disease Subjects
- Quantitative Imaging of Brain Glymphatic Function in Humans
- Novel therapeutic approaches for Parkinson’s disease by targeting brain cholesterol homeostasis
- The history of light therapy in hospital physiotherapy and medicine with emphasis on Australia: Evolution into novel areas of practice
- Neuroimmune connections between corticotropin-releasing hormone and mast cells: novel strategies for the treatment of neurodegenerative diseases
- Involvement of Astrocytes and microRNA Dysregulation in Neurodegenerative Diseases: From Pathogenesis to Therapeutic Potential
- ATH-1017 Treatment in Subjects With Parkinson’s Disease Dementia
- Perampanel Inhibits alpha-Synuclein Transmission in Parkinson’s Disease Models
- Anti-Apoptotic and Anti-Inflammatory Role of Trans epsilon-Viniferin in a Neuron-Glia Co-Culture Cellular Model of Parkinson’s Disease
- Therapeutic Advances in Diabetes, Autoimmune, and Neurological Diseases
- Hunting for Familial Parkinson’s Disease Mutations in the Post Genome Era
- The Novel Alpha-2 Adrenoceptor Inhibitor Beditin Reduces Cytotoxicity and Huntingtin Aggregates in Cell Models of Huntington’s Disease
- Personalized Approach to the Role of Endoscopic Ultrasound in the Diagnosis and Management of Pancreaticobiliary Malignancies
- Novel Pulmonary Delivery of Antiviral Drugs for Treating COVID-19 in Patients with Parkinson’s Disease
- Development of CVN424: a selective and novel GPR6 inverse agonist effective in models of Parkinson’s Disease
- A Study to Assess Pharmacokinetic Profiles of LY03003 and Neupro
- Individual Magnetoencephalography Response Profiles to Short-Duration L-Dopa in Parkinson’s Disease
- Neuroimaging evaluation of deep brain stimulation in the treatment of representative neurodegenerative and neuropsychiatric disorders
- Gliadin Sequestration as a Novel Therapy for Celiac Disease: A Prospective Application for Polyphenols
- Prevention of MEK-ERK-1/2 hyper-activation underlines the neuroprotective effect of Glycyrrhiza glabra L. (Yashtimadhu) against rotenone-induced cellular and molecular aberrations
- A novel Phosphodiesterase 1 inhibitor reverses L-Dopa-induced dyskinesia, but not motivation deficits, in monkeys
- Generation and Cultivation of Transgene-Free Macaque and Baboon iPSCs Under Chemically Defined Conditions
- Case Report: Ziprasidone induced neuroleptic malignant syndrome
- CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice
- Do peripheral immune and neurotrophic markers correlate with motor severity of Parkinson’s disease?
- Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones
- Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes
- Involvement of the gut-brain axis in neurological disorders
- Parkinson’s Disease With Mild Cognitive Impairment Treated With Nicotinic Agonist Drug
- Analysis of genetic risk factors in Japanese patients with Parkinson’s disease
- Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease
- Discovery of novel dual adenosine A1/A2A receptor antagonists using deep learning, pharmacophore modeling and molecular docking
- Molecular Mechanisms Underlying Synaptic and Axon Degeneration in Parkinson’s Disease
- Detection of pathological alpha-synuclein aggregates in human iPSC-derived neurons and tissue
- A Study to Assess the Safety and Tolerability of Surgical Implant of MSK-DA01 Cells for Advanced Parkinson’s Disease
- Targeting Age-Related Neurodegenerative Diseases by AAV-Mediated Gene Therapy
- Proteomics for Target Identification in Psychiatric and Neurodegenerative Disorders
- Long Term Safety and Efficacy Study of ProSavin in Parkinson’s Disease
- Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body
- Celiac Disease Causes Epithelial Disruption and Regulatory T Cell Recruitment in the Oral Mucosa
- Voltage-Gated Ca(2+) Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson’s Disease?
- Exogenous Alpha-Synuclein Evoked Parkin Downregulation Promotes Mitochondrial Dysfunction in Neuronal Cells. Implications for Parkinson’s Disease Pathology
- Neurotransmitters, Cell Types, and Circuit Mechanisms of Motor Skill Learning and Clinical Applications
- Membrane Interactions of α-Synuclein Revealed by Multiscale Molecular Dynamics Simulations, Markov State Models, and NMR
- Loss of GSK-3β mediated phosphorylation in HtrA2 contributes to uncontrolled cell death with Parkinsonian phenotype
- A selective NLRP3 inflammasome inhibitor attenuates behavioral deficits and neuroinflammation in a mouse model of Parkinson’s disease
- Kaempferol alleviates LD-mitochondrial damage by promoting autophagy: Implications in Parkinson’s disease
- Technology Integration Methods for Bi-directional Brain-computer Interfaces and XR-based Interventions
- Uniting homeostatic plasticity and exosome biology: A revision of the conceptual framework for drug discovery in neurodegenerative diseases?
- Preliminary Study of Piclozotan in Patients With Motor Complications Associated With Parkinson’s Disease
- Role of microgliosis, oxidative stress and associated neuroinflammation in the pathogenesis of Parkinson’s disease: The therapeutic role of Nrf2 activators
- GluN2B/N-methyl-D-aspartate receptor antagonists: Advances in design, synthesis, and pharmacological evaluation studies
- Multifunctional Nanoprobe for the Delivery of Therapeutic siRNA and Real-Time Molecular Imaging of Parkinson’s Disease Biomarkers
- The Role of the Inflammasome in Neurodegenerative Diseases
- Therapeutic Potential of alphaS Evolvability for Neuropathic Gaucher Disease
- High-Throughput Screening Platforms in the Discovery of Novel Drugs for Neurodegenerative Diseases
- A LRRK2 GTP Binding Inhibitor, 68, Reduces LPS-Induced Signaling Events and TNF-α Release in Human Lymphoblasts
- SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders
- MST for Parkinson’s Disease
- Spectral signatures of L-DOPA-induced dyskinesia depend on L-DOPA dose and are suppressed by ketamine
- Recent advances in understanding and treatment of Parkinson’s disease
- Biomaterials in the Treatment of Parkinson’s Disease
- Parkinson’s Disease Therapy Using Cell Technology
- The Gut-Brain Axis: Two Ways Signaling in Parkinson’s Disease
- Nabilone for Non-motor Symptoms in Parkinson’s Disease
- Nabilone for Non-motor Symptoms in Parkinson’s Disease
- Assessing the Pharmacokinetics, Safety, Tolerability and Efficacy of Continuous Oral Levodopa Via the DopaFuse® Delivery System in Parkinson’s Disease Patients
- A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson’s Disease
- Molecular Mechanisms Underlying Reciprocal Interactions Between Sleep Disorders and Parkinson’s Disease
- The bile acid TUDCA and neurodegenerative disorders: An overview
- Sleep electroencephalographic asymmetry in Parkinson’s disease patients before and after deep brain stimulation
- High-throughput behavioral screen in C. elegans reveals Parkinson’s disease drug candidates
- Novel targeted therapies for Parkinson’s disease
- Novel method for screening functional antibody with comprehensive analysis of its immunoliposome
- Motor thalamic deep brain stimulation alters cortical activity and shows therapeutic utility for treatment of Parkinson’s disease symptoms in a rat model
- Amantadine: reappraisal of the timeless diamond-target updates and novel therapeutic potentials
- The Efficacy of Ketogenic Therapies in the Clinical Management of People with Neurodegenerative Disease: A Systematic Review
- Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide dual receptor agonist DA-CH5 is superior to exendin-4 in protecting neurons in the 6-hydroxydopamine rat Parkinson model
- ERRγ ligand HPB2 upregulates BDNF-TrkB and enhances dopaminergic neuronal phenotype
- Extracellular Vesicles in the Treatment of Parkinson’s Disease: A Review
- Precompetitive Consensus Building to Facilitate the Use of Digital Health Technologies to Support Parkinson Disease Drug Development through Regulatory Science
- Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases?
- Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo
- Therapies for Genetic Forms of Parkinson’s Disease: Systematic Literature Review
- Parkinson patients have a presynaptic serotonergic deficit: A dynamic deep brain stimulation PET study
- Androgen deprivation therapy for prostate cancer and the risk of autoimmune diseases
- Metabotropic glutamate receptor 5 inhibits alpha-synuclein-induced microglia inflammation to protect from neurotoxicity in Parkinson’s disease
- Targeting Mitochondrial Impairment in Parkinson’s Disease: Challenges and Opportunities
- Mitophagy impairment in neurodegenerative diseases: Pathogenesis and therapeutic interventions
- Sigma-2 receptor antagonists rescue neuronal dysfunction induced by Parkinson’s patient brain-derived alpha-synuclein
- Urinary proteome profiling for stratifying patients with familial Parkinson’s disease
- Comprehensive metabolic profiling of Parkinson’s disease by liquid chromatography-mass spectrometry
- Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration
- Neuroprotective potential of cinnamon and its metabolites in Parkinson’s disease: Mechanistic insights, limitations, and novel therapeutic opportunities
- From Transcriptomics to Treatment in Inherited Optic Neuropathies
- Recent findings leading to the discovery of selective dopamine D4 receptor ligands for the treatment of widespread diseases
- Target Molecules of STIM Proteins in the Central Nervous System
- Botulinum Toxin in Movement Disorders: An Update
- Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease
- Promising drug targets and associated therapeutic interventions in Parkinson’s disease
- Reverse engineering Lewy bodies: how far have we come and how far can we go?
- Regulation of neuronal bioenergetics as a therapeutic strategy in neurodegenerative diseases
- Dihydroquinazolines enhance 20S proteasome activity and induce degradation of α-synuclein, an intrinsically disordered protein associated with neurodegeneration
- Contribution of astrocytes to neuropathology of neurodegenerative diseases
- Can the interplay between autophagy and apoptosis be targeted as a novel therapy for Parkinson’s disease?
- 14-3-3 Proteins: Novel Pharmacological Targets in Neurodegenerative Diseases
- A Qualitative Analysis of Ethical Perspectives on Recruitment and Consent for Human Intracranial Electrophysiology Studies
- Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study
- HMGA1 Induction of miR-103/107 Forms a Negative Feedback Loop to Regulate Autophagy in MPTP Model of Parkinson’s Disease
- Mitochondrial dysfunction in neurodegenerative diseases: A focus on iPSC-derived neuronal models
- Exit Gluten-Free and Enter Low FODMAPs: A Novel Dietary Strategy to Reduce Gastrointestinal Symptoms in Athletes
- Evidence and perspectives of cell senescence in neurodegenerative diseases
- Nondietary Therapies for Celiac Disease
- Pigment Epithelium-Derived Factor Affects Angiogenesis in Celiac Disease
- GardeninA confers neuroprotection against environmental toxin in a Drosophila model of Parkinson’s disease
- Demystifying autoimmune small bowel enteropathy
- Past, Present, and Future of Non-invasive Brain Stimulation Approaches to Treat Cognitive Impairment in Neurodegenerative Diseases: Time for a Comprehensive Critical Review
- Ribes orientale: A novel therapeutic approach targeting rheumatoid arthritis with reference to pro-inflammatory cytokines, inflammatory enzymes and anti-inflammatory cytokines
- Chronic diarrhoea in adults: what not to miss
- Switch from tablet levothyroxine to oral solution resolved reduced absorption by intestinal parasitosis
- Periphery and brain, innate and adaptive immunity in Parkinson’s disease
- The gliadin-CFTR connection: new perspectives for the treatment of celiac disease
- Advances in Molecular Mechanisms of Wheat Allergenicity in Animal Models: A Comprehensive Review
- The Role of α-Synuclein in Methamphetamine-Induced Neurotoxicity
- Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk
- RNA sequencing of intestinal mucosa reveals novel pathways functionally linked to celiac disease pathogenesis
- Synthesis of Double Interfering Biodegradable Nano-MgO Micelle Composites and Their Effect on Parkinson’s Disease
- Human gut derived-organoids provide model to study gluten response and effects of microbiota-derived molecules in celiac disease
- Breaking Down Barriers: How Understanding Celiac Disease Pathogenesis Informed the Development of Novel Treatments
- microRNAs: Novel Markers in Diagnostics and Therapeutics of Celiac Disease
- Novel Nondietary Therapies for Celiac Disease
- Evaluating Novel RXR Agonists That Induce ApoE and Tyrosine Hydroxylase in Cultured Human Glioblastoma Cells
- Dermatitis Herpetiformis: Novel Perspectives
- Dysregulation of PGC-1alpha-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities
- Association study identified biologically relevant receptor genes with synergistic functions in celiac disease
- Genetic and phenotypic characterization of indolent T-cell lymphoproliferative disorders of the gastrointestinal tract
- Digital Progression Biomarkers as Novel Endpoints in Clinical Trials: A Multistakeholder Perspective
- Molecular mechanisms of 33-mer gliadin peptide oligomerisation
- Neuroprotective potential of cinnamon and its metabolites in Parkinson’s disease: Mechanistic insights, limitations, and novel therapeutic opportunities
- The Gut Microbiota in Celiac Disease and probiotics
- Novel targets for drug discovery in celiac disease
- Role of Liver Growth Factor (LGF) in Parkinson’s Disease: Molecular Insights and Therapeutic Opportunities
- Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: a systematic review
- To Be or Not to Be a Pathogen: Candida albicans and Celiac Disease
- All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases
- Could Cannabidiol Be a Treatment for Coronavirus Disease-19-Related Anxiety Disorders?
- Oats as a Safe Alternative to Triticeae Cereals for People Suffering from Celiac Disease? A Review
- Refractory Celiac Disease
- Role of extracellular vesicles in neurodegenerative diseases
- An Energy Optimization Strategy Based on the Perfect Conformation of Prolyl Endopeptidase for Improving Catalytic Efficiency
- Reinventing the nutraceutical value of gluten: The case of l-theanine-gluten as a potential alternative to the gluten exclusion diet in celiac disease
- Deregulation of miRNAs-cMYC circuits is a key event in refractory celiac disease type-2 lymphomagenesis
- A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function
- Deciphering short stature in children
- Rationally engineered prolyl endopeptidases from Sphingomonas capsulata with improved hydrolytic activity towards pathogenic peptides of celiac diseases
- Gluten Degrading Enzymes for Treatment of Celiac Disease
- Updated but not outdated “Gliadin”: A plant protein in advanced pharmaceutical nanotechnologies
- Fecal microRNAs as Innovative Biomarkers of Intestinal Diseases and Effective Players in Host-Microbiome Interactions
- Maternal bacteria to correct abnormal gut microbiota in babies born by C-section
- Interventional pain management in patients with cancer-related pain
- The Role of Resilience in Irritable Bowel Syndrome, Other Chronic Gastrointestinal Conditions, and the General Population
- Probiomimetics-Novel Lactobacillus-Mimicking Microparticles Show Anti-Inflammatory and Barrier-Protecting Effects in Gastrointestinal Models
- Sprouted oat as a potential gluten-free ingredient with enhanced nutritional and bioactive properties
- Artificial intelligence in celiac disease
- Exploring celiac disease candidate pathways by global gene expression profiling and gene network cluster analysis
- The use of peripheral blood mononuclear cells in celiac disease diagnosis and treatment
- Coeliac disease in childhood: An overview
- Posttranslational modifications as therapeutic targets for intestinal disorders
- Non-invasive peripheral focused ultrasound neuromodulation of the celiac plexus ameliorates symptoms in a rat model of inflammatory bowel disease
- Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells
- Genome-wide genetic links between amyotrophic lateral sclerosis and autoimmune diseases
- Immunophenotypic Spectrum and Genomic Landscape of Refractory Celiac Disease Type II
- Novel Therapeutic Strategies for Celiac Disease
- Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies.
- Could Cannabidiol Be a Treatment for Coronavirus Disease-19-Related Anxiety Disorders?
- Role of extracellular vesicles in neurodegenerative diseases.
- A Study of E2027 in Participants With Dementia With Lewy Bodies (DLB) or Parkinson’s Disease Dementia (PDD) With or Without Amyloid Copathology
- Role of Liver Growth Factor (LGF) in Parkinson’s Disease: Molecular Insights and Therapeutic Opportunities.
- Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: a systematic review.
- Characterization of information processing in the subthalamic area of Parkinson’s patients.
- Effects of the probiotic formulation SLAB51 in in vitro and in vivo Parkinson’s disease models.
- A Efficacy, Safety and Pharmacokinetic Study of XP21279 and Sinemet® in Parkinson’s Disease Subjects
- Open-label Trial in Parkinson’s Disease (PD)
- Advanced MRI techniques for transcranial high intensity focused ultrasound targeting.
- Digital Progression Biomarkers as Novel Endpoints in Clinical Trials: A Multistakeholder Perspective.
- Gut microbiome a promising target for management of respiratory diseases.
- Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities.
- Evaluating Novel RXR Agonists That Induce ApoE and Tyrosine Hydroxylase in Cultured Human Glioblastoma Cells.
- Study To Assess Adverse Events and Change in Disease Activity Of 24-hour Continuous Subcutaneous Infusion Of ABBV-951 In Adult Participants With Advanced Parkinson’s Disease
- Novel Therapeutic Strategies for Celiac Disease.
- Synthesis of Double Interfering Biodegradable Nano-MgO Micelle Composites and Their Effect on Parkinson’s Disease.
- ‘Recoupling’ the attentional and motor control of preparatory postural adjustments to overcome freezing of gait in Parkinson’s.
- Past, Present, and Future of Non-invasive Brain Stimulation Approaches to Treat Cognitive Impairment in Neurodegenerative Diseases: Time for a Comprehensive Critical Review.
- Periphery and brain, innate and adaptive immunity in Parkinson’s disease.
- The Role of α-Synuclein in Methamphetamine-Induced Neurotoxicity.
- GardeninA confers neuroprotection against environmental toxin in a Drosophila model of Parkinson’s disease.
- Evidence and perspectives of cell senescence in neurodegenerative diseases.
- Genome-wide genetic links between amyotrophic lateral sclerosis and autoimmune diseases.
- Immunophenotypic Spectrum and Genomic Landscape of Refractory Celiac Disease Type II.
- HMGA1 Induction of miR-103/107 Forms a Negative Feedback Loop to Regulate Autophagy in MPTP Model of Parkinson’s Disease.
- Amantadine and L-DOPA-induced Dyskinesia in Early Parkinson’s Disease
- Mitochondrial dysfunction in neurodegenerative diseases: A focus on iPSC-derived neuronal models.
- A Study of CST-103 Co-administered With CST-107 in Subjects With Neurodegenerative Disorders
- Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study.
- A Qualitative Analysis of Ethical Perspectives on Recruitment and Consent for Human Intracranial Electrophysiology Studies.
- Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells.
- Follow Up Safety Study of SCH 420814 in Subjects With Parkinson’s Disease (P05175)
- 14-3-3 Proteins: Novel Pharmacological Targets in Neurodegenerative Diseases.
- Contribution of astrocytes to neuropathology of neurodegenerative diseases.
- Can the interplay between autophagy and apoptosis be targeted as a novel therapy for Parkinson’s disease?
- Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease.
- Promising drug targets and associated therapeutic interventions in Parkinson’s disease.
- Dihydroquinazolines enhance 20S proteasome activity and induce degradation of α-synuclein, an intrinsically disordered protein associated with neurodegeneration.
- Non-invasive peripheral focused ultrasound neuromodulation of the celiac plexus ameliorates symptoms in a rat model of inflammatory bowel disease.
- Microbiota Modification for the Treatment of Motor Complication of Parkinson´s Disease
- Recent studies on NCLX in health and diseases.
- From Transcriptomics to Treatment in Inherited Optic Neuropathies.
- Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics.
- Neuroprotective potential of cinnamon and its metabolites in Parkinson’s disease: Mechanistic insights, limitations, and novel therapeutic opportunities.
- Comprehensive metabolic profiling of Parkinson’s disease by liquid chromatography-mass spectrometry.
- Sigma-2 receptor antagonists rescue neuronal dysfunction induced by Parkinson’s patient brain-derived α-synuclein.
- Urinary proteome profiling for stratifying patients with familial Parkinson’s disease.
- Study of the Fecal Microbiome in Patients With Parkinson’s Disease
- Mitophagy Impairment in Neurodegenerative Diseases: Pathogenesis and Therapeutic Interventions.
- Targeting Mitochondrial Impairment in Parkinson’s Disease: Challenges and Opportunities.
- Quantum dot conjugated saporin activates microglia and induces selective substantia nigra degeneration.
- TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)
- Parkinson patients have a presynaptic serotonergic deficit: A dynamic deep brain stimulation PET study.
- Metabotropic glutamate receptor 5 inhibits α-synuclein-induced microglia inflammation to protect from neurotoxicity in Parkinson’s disease.
- Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo.
- Therapies for Genetic Forms of Parkinson’s Disease: Systematic Literature Review.
- Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases?
- Blood biomarkers with Parkinson’s disease clusters and prognosis: The oxford discovery cohort.
- Extracellular Vesicles in the Treatment of Parkinson’s Disease: A Review.
- Precompetitive Consensus Building to Facilitate the Use of Digital Health Technologies to Support Parkinson Disease Drug Development through Regulatory Science.
- 18F-DOPA II – PET Imaging Optimization
- Botulinum Toxin in Movement Disorders: An Update.
- Novel drug delivery systems of β2 adrenoreceptor agonists to suppress SNCA gene expression and mitochondrial oxidative stress in Parkinson’s disease management.
- Reverse engineering Lewy bodies: how far have we come and how far can we go?
- Regulation of neuronal bioenergetics as a therapeutic strategy in neurodegenerative diseases.
- Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide dual receptor agonist DA-CH5 is superior to exendin-4 in protecting neurons in the 6-hydroxydopamine rat Parkinson model.
- ERRγ ligand HPB2 upregulates BDNF-TrkB and enhances dopaminergic neuronal phenotype.
- Novel approaches to counter protein aggregation pathology in Parkinson’s disease.
- Target Molecules of STIM Proteins in the Central Nervous System.
- Recent findings leading to the discovery of selective dopamine D4 receptor ligands for the treatment of widespread diseases.
- Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.
- Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration.
- Posttranslational modifications as therapeutic targets for intestinal disorders.
- Identification of antiparkinsonian drugs in the 6-hydroxydopamine zebrafish model.
- Dynamin-related protein 1: A protein critical for mitochondrial fission, mitophagy, and neuronal death in Parkinson’s disease.
- Novel Associations of BST1 and LAMP3 with Rapid Eye Movement Sleep Behavior Disorder.
- Study on the Safety, Tolerance and Pharmacokinetics of Phenlarmide Tablets
- The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson’s disease.
- StimVision v2: Examples and Applications in Subthalamic Deep Brain Stimulation for Parkinson’s Disease.
- Iron Dysregulation and Inflammagens Related to Oral and Gut Health Are Central to the Development of Parkinson’s Disease.
- Cannabidiol as a Therapeutic Target: Evidence of its Neuroprotective and Neuromodulatory Function in Parkinson’s Disease.
- Fisetin Regulates Gut Microbiota and Exerts Neuroprotective Effect on Mouse Model of Parkinson’s Disease.
- Huang Lian Jie Du Tang attenuates paraquat-induced mitophagy in human SH-SY5Y cells: A traditional decoction with a novel therapeutic potential in treating Parkinson’s disease.
- Relative Bioavailability and Bioequivalence of Opicapone
- Safety, Tolerability, Pharmacokinetics and Efficacy Study of Radotinib in Parkinson’s Disease
- Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study.
- Cell Senescence in Neuropathology: a Focus on Neurodegeneration and Tumours.
- The Stanford Parkinson’s Disease Plasma Study
- Self-inflating floating nanofiber membranes for controlled drug delivery.
- The Effect of Intranasal Insulin on Motor and Non-motor Symptoms in Parkinson’s Disease Patients
- MPTP-induced mouse model of Parkinson’s disease: A promising direction of therapeutic strategies.
- Glutathione peroxidase-1 and neuromodulation: novel potentials of an old enzyme.
- Establishment of Clinical Basis for Hematopoietic Growth Factors Therapy in Brain Injury
- A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of anle138b in Parkinson’s Disease
- Evaluation of the Efficacy and Safety of AFQ056 in Parkinson’s Patients With L-dopa Induced Dyskinesias
- Innovative Applications of MR-Guided Focused Ultrasound for Neurological Disorders.
- Design of a virtual longitudinal observational study in Parkinson’s disease (AT-HOME PD).
- Recent advances in dopaminergic strategies for the treatment of Parkinson’s disease.
- A New Day: The Role of Telemedicine in Reshaping Care for Persons With Movement Disorders.
- Subthalamic Nucleus Deep Brain Stimulation Modulates 2 Distinct Neurocircuits.
- Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease.
- Cancer and Parkinson’s Disease: Common Targets, Emerging Hopes.
- Interventional pain management in patients with cancer-related pain.
- Distinct subthalamic coupling in the ON state describes motor performance in Parkinson’s disease.
- The role of the gut microbiota in the pathophysiology of mental and neurological disorders.
- Neuromodulation Options and Patient Selection for Parkinson’s Disease.
- Nanotheranostic agents for neurodegenerative diseases.
- PET Radiopharmaceuticals for Alzheimer’s Disease and Parkinson’s Disease Diagnosis, the Current and Future Landscape.
- Highly-selective µ-opioid receptor antagonism does not block L-DOPA-induced dyskinesia in a rodent model.
- Smart neuromodulation in movement disorders.
- Industrial perspectives on brain-computer interface technology.
- Mdm2 enhances ligase activity of parkin and facilitates mitophagy.
- Emerging novel approaches to drug research and diagnosis of Parkinson’s disease.
- Extracellular vesicles – propagators of neuropathology and sources of potential biomarkers and therapeutics for neurodegenerative diseases.
- Targeting Microglia for Therapy of Parkinson’s Disease by Using Biomimetic Ultrasmall Nanoparticles.
- Aging-related modifications to G protein-coupled receptor signaling diversity.
- Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain
- Extracellular Vesicles and Damage-Associated Molecular Patterns: A Pandora’s Box in Health and Disease.
- Genetic mechanisms of critical illness in Covid-19.
- Challenges and translational considerations of mesenchymal stem/stromal cell therapy for Parkinson’s disease.
- 18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety
- Cerebral sterile inflammation in neurodegenerative diseases.
- A cysteine near the C-terminus of UCH-L1 is dispensable for catalytic activity but is required to promote AKT phosphorylation, eIF4F assembly, and malignant B-cell survival.
- New Insights into Immune-Mediated Mechanisms in Parkinson’s Disease.
- Closed-loop neuromodulation for clustering neuronal populations.
- A 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson’s Disease
- PasoDoble, a Proposed Dance/Music for People With Parkinson’s Disease and Their Caregivers.
- Current Evidence for a Bidirectional Loop Between the Lysosome and Alpha-Synuclein Proteoforms.
- Liver Growth Factor “LGF” as a Therapeutic Agent for Alzheimer’s Disease.
- Extracellular Vesicle-Based Therapeutics: Preclinical and Clinical Investigations.
- Entacapone promotes hippocampal neurogenesis in mice.
- Auricular Muscle Zone Stimulation for Parkinson Disease
- A Safety and Pharmacokinetics Study of UCB7853 in Healthy Study Participants and Study Participants With Parkinson’s Disease (PD)
- Dual Frequency Stimulation in Parkinson’s Disease
- Amorphous Ropinirole-Loaded Mucoadhesive Buccal Film: A Potential Patient-Friendly Tool to Improve Drug Pharmacokinetic Profile and Effectiveness.
- DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease.
- Using machine learning-based analytics of daily activities to identify modifiable risk factors for falling in Parkinson’s disease.
- Neuroprotective and Neurotoxic Effects of Endocannabinoid-like compounds, N-Arachidonoyl Dopamine and N-Docosahexaenoyl Dopamine in Differentiated Cultures of Induced Pluripotent Stem Cells Derived from Patients with Parkinson’s Disease.
- A new MAP-Rasagiline conjugate reduces α-synuclein inclusion formation in a cell model.
- Ameliorative effects of a phosphodiesterase 10A inhibitor, MR1916 on L-DOPA-induced dyskinesia in parkinsonian rats.
- Proteomic Profiling of Mitochondrial-Derived Vesicles in Brain Reveals Enrichment of Respiratory Complex Sub-assemblies and Small TIM Chaperones.
- Immune-associated biomarkers for early diagnosis of Parkinson’s disease based on hematological lncRNA-mRNA co-expression.
- Spectral guided sparse inverse covariance estimation of metabolic networks in Parkinson’s disease.
- Characterization of EEG Data Revealing Relationships With Cognitive and Motor Symptoms in Parkinson’s Disease: A Systematic Review.
- Sprouted oat as a potential gluten-free ingredient with enhanced nutritional and bioactive properties.
- Virtual screening and drug repurposing experiments to identify potential novel selective MAO-B inhibitors for Parkinson’s disease treatment.
- Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson’s Disease
- Palliative care and Parkinson’s disease: outpatient needs and models of care over the disease trajectory.
- Inhibition of copper transporter 1 prevents α-synuclein pathology and alleviates nigrostriatal degeneration in AAV-based mouse model of Parkinson’s disease.
- BEN-2001 in Parkinson Disease Patients With Excessive Daytime Sleepiness
- A critical review of apomorphine hydrochloride sublingual film for the treatment of Parkinson’s disease ‘OFF’ Episodes.
- An Open-label Safety Study of Pimavanserin in Parkinson’s Disease Patients
- A Study to Evaluate SAGE-217 in Participants With Parkinson’s Disease
- Therapeutic Path to Double Knockout: Investigating the Selective Dual-Inhibitory Mechanisms of Adenosine Receptors A1 and A2 by a Novel Methoxy-Substituted Benzofuran Derivative in the Treatment of Parkinson’s Disease.
- Antiferroptotic Activity of Phenothiazine Analogues: A Novel Therapeutic Strategy for Oxidative Stress Related Disease.
- A 12-week Randomized Study to Evaluate Oral Istradefylline in Subjects With Moderate to Severe Parkinson’s Disease
- Orthostatic Dysregulation and Associated Gastrointestinal Dysfunction in Parkinson’s Disease -Treatment
- Study of the Symptomatic Effects of Nocturnal Sodium Oxybate in Parkinson’s Disease
- Recent Insights on the Role of PPAR-β/δ in Neuroinflammation and Neurodegeneration, and Its Potential Target for Therapy.
- Parkinson’s Disease Master Regulators on Substantia Nigra and Frontal Cortex and Their Use for Drug Repositioning.
- Development and evaluation of a novel music-based therapeutic device for upper extremity movement training: A pre-clinical, single-arm trial.
- Approaches to Disease Modification for Parkinson’s Disease: Clinical Trials and Lessons Learned.
- Vercise Implantable Stimulator for Treating Parkinson’s Disease
- Dual-task Augmented Reality Treatment for Parkinson’s Disease
- Coeliac disease in childhood: An overview.
- Chemical compounds with a neuroprotective effect from the seeds of Celosia argentea L.
- Dopamine, Alpha-Synuclein, and Mitochondrial Dysfunctions in Parkinsonian Eyes.
- E3 Ubiquitin Ligases in Neurological Diseases: Focus on Gigaxonin and Autophagy.
- The Role of Exosomal microRNAs and Oxidative Stress in Neurodegenerative Diseases.
- Current updates in transdermal therapeutic systems and their role in neurological disorders.
- In-silico prediction of the beta carboline alkaloids Harmine and Harmaline as potent drug candidates for the treatment of Parkinson’s disease.
- The Library Derived 4554W Peptide Inhibits Primary Nucleation of α-Synuclein.
- Therapeutics potentiating microglial p21-Nrf2 axis can rescue neurodegeneration caused by neuroinflammation.
- Increased telomerase improves motor function and alpha-synuclein pathology in a transgenic mouse model of Parkinson’s disease associated with enhanced autophagy.
- A Study to Evaluate the Pharmacokinetics and Safety of LY03003 in Patients With Advanced-stage PD
- A Clinical Trial to Evaluate the Pharmacodynamics/Pharmacokinetics and Safety of LY03003 in Early PD Patients
- Neuroimaging Advances in Parkinson’s Disease and Atypical Parkinsonian Syndromes.
- Mitochondrial hyperactivity as a potential therapeutic target in Parkinson’s disease.
- Open-Label Phase 3 Study to Examine the Long-Term Safety, Tolerability and Efficacy of APL-130277 for the Acute Treatment of “OFF” Episodes in Patients With Parkinson’s Disease
- Effects of PR Oxycodone and of Levodopa, vs Placebo, on Central Neuropathic Pain in Parkinson’s Disease
- A Study to Evaluate the Human Tolerance and Pharmacokinetics of LY03003
- Recuperative effect of metformin loaded polydopamine nanoformulation promoting EZH2 mediated proteasomal degradation of phospho-α-synuclein in Parkinson’s disease model.
- Curcumin Prevents Neuroinflammation by Inducing Microglia to Transform into the M2-phenotype via CaMKKβ-dependent Activation of the AMP-Activated Protein Kinase Signal Pathway.
- Calbindin-D9k is a Novel Risk Gene for Neurodegenerative Disease.
- Activation of Sirt1/PGC1α pathway attenuates neuroinflammation injury in Parkinson’s disease.
- Molecular landscape of long noncoding RNAs in brain disorders.
- Pivotal Role of Fyn Kinase in Parkinson’s Disease and Levodopa-Induced Dyskinesia: a Novel Therapeutic Target?
- The use of peripheral blood mononuclear cells in celiac disease diagnosis and treatment.
- Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC122505MsOH Tablets in Healthy Adult Subjects
- High-Specificity Digital Architecture for Real-Time Recognition of Loss of Balance Inducing Fall.
- Slowed Movement Stopping in Parkinson’s Disease and Focal Dystonia is Improved by Standard Treatment.
- Food supplements based on palmitoylethanolamide plus hydroxytyrosol from olive tree or Bacopa monnieri extracts for neurological diseases.
- A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics.
- Protective effect of thioredoxin reductase 1 in Parkinson’s disease.
- Do the Bugs in Your Gut Eat Your Memories? Relationship between Gut Microbiota and Alzheimer’s Disease.
- Neuronal Bmi-1 is critical for melatonin induced ubiquitination and proteasomal degradation of α-synuclein in experimental Parkinson’s disease models.
- Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients
- 2-Hydroxy-4-Methylbenzoic Anhydride Inhibits Neuroinflammation in Cellular and Experimental Animal Models of Parkinson’s Disease.
- Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients
- Metabolic Profiling of CSF from People Suffering from Sporadic and LRRK2 Parkinson’s Disease: A Pilot Study.
- Effectiveness of the Iron Chelator CN128 in Mitigating the Formation of Dopamine Oxidation Products Associated with the Progression of Parkinson’s Disease.
- Combatting Nitrosative Stress and Inflammation with Novel Substituted Triazinoindole Inhibitors of Aldose Reductase in PC12 Cells Exposed to 6-Hydroxydopamine Plus High Glucose.
- Autophagic receptor p62 protects against glycation-derived toxicity and enhances viability.
- Automated Quantification of Mitochondrial Fragmentation in an In Vitro Parkinson’s Disease Model.
- Effects of tDCS Combined With Therapeutic Exercises in Patients With Parkinson’s Disease.
- 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson’s Disease
- Role of Dietary Antioxidants in Neurodegenerative Diseases: Where are We Standing?
- Stem Cell-Based Therapies for Parkinson Disease.
- A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson’s disease.
- Nanoparticles for drug delivery in Parkinson’s disease.
- “Developing new treatments in partnership for Primary Mitochondrial Disease: what does industry need from academics, and what do academics need from industry?”
- Perspective: Phase Amplitude Coupling-Based Phase-Dependent Neuromodulation in Parkinson’s Disease.
- Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases.
- Miro (Mitochondrial Rho GTPase), a key player of Mitochondrial axonal transport and Mitochondrial dynamics in Neurodegenerative diseases.
- Precision Medicine in Neurology: The Inspirational Paradigm of Complement Therapeutics.
- Dermatitis Herpetiformis: Novel Perspectives.
- Identification of Molecular Network Associated with Neuroprotective Effects of Yashtimadhu (Glycyrrhiza glabra L.) by Quantitative Proteomics of Rotenone-Induced Parkinson’s Disease Model.
- Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function.
- Cholesterol metabolism and brain injury in neonatal encephalopathy.
- Identification of Specific Circular RNA Expression Patterns and MicroRNA Interaction Networks in Mesial Temporal Lobe Epilepsy.
- Upregulation of Cellular Palmitoylation Mitigates α-Synuclein Accumulation and Neurotoxicity.
- Clinical Trial to Evaluate the Safety and Tolerability of Hydrogen in Patients With Parkinson’s Disease
- Research progress on adenosine in central nervous system diseases.
- FTY720-Mitoxy reduces synucleinopathy and neuroinflammation, restores behavior and mitochondria function, and increases GDNF expression in Multiple System Atrophy mouse models.
- Demonstration of Kinematic-Based Closed-loop Deep Brain Stimulation for Mitigating Freezing of Gait in People with Parkinson’s Disease.
- Quantification of Parkinson’s Disease Motor Symptoms: A Wireless Motion Sensing Approach.
- Dysfunction of the Microbiota-Gut-Brain Axis in Neurodegenerative Disease: The Promise of Therapeutic Modulation With Prebiotics, Medicinal Herbs, Probiotics, and Synbiotics.
- An Extension Study to Assess the Safety, Tolerability and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson’s Disease and Persistent Motor-Complications Despite Optimized Treatment With Available Anti-Parkinsonian Medications
- Telerehabilitation for Parkinson’s Disease
- Nanomedicine against Alzheimer’s and Parkinson’s disease.
- Current and emerging therapeutic targets for Parkinson’s disease.
- Serotonergic System Impacts Levodopa Response in Early Parkinson’s and Future Risk of Dyskinesia.
- A Study of Weekly Subcutaneous Injections of SER-214 in Subjects With Parkinson’s Disease (PD), to Determine the Safety, Tolerability and Pharmacokinetic (PK) Profile of SER-214
- Performance of Force-Field- and Machine Learning-Based Scoring Functions in Ranking MAO-B Protein-Inhibitor Complexes in Relevance to Developing Parkinson’s Therapeutics.
- A case report of delayed diagnosis of danon disease: Caused by a newly recognized mutation in the lysosome-associated membrane protein-2 gene.
- A case study of foliglurax, the first clinical mGluR4 PAM for symptomatic treatment of Parkinson’s disease: Translational gaps or a failing industry innovation model?
- Trial of Ursodeoxycholic Acid (UDCA) for Parkinson’s Disease: The “UP” Study
- to Evaluate the Safety, Tolerability and Pharmacokinetics of Four Formulations of LY03009 in Healthy Volunteers
- The Multimodal Serotonergic Agent Vilazodone Inhibits L-DOPA-Induced Gene Regulation in Striatal Projection Neurons and Associated Dyskinesia in an Animal Model of Parkinson’s Disease.
- Diet, Microbiota and Brain Health: Unraveling the Network Intersecting Metabolism and Neurodegeneration.
- Emerging role of S100B protein implication in Parkinson’s disease pathogenesis.
- Perspective: Evolution of Control Variables and Policies for Closed-Loop Deep Brain Stimulation for Parkinson’s Disease Using Bidirectional Deep-Brain-Computer Interfaces.
- Biomarker Assessments of Leukine During Treatment of Parkinson’s Disease
- PK Study of WD-1603 in Healthy Subjects
- eBrain: a Three Dimensional Simulation Tool to Study Drug Delivery in the Brain.
- Synthesis and preliminary studies of 11C-labeled tetrahydro-1,7-naphthyridine-2-carboxamides for PET imaging of metabotropic glutamate receptor 2.
- Acute Effects of Medium Chain Triglyceride (MCT) Nutritional Ketosis on Parkinson’s Disease (PD) Symptoms and Biomarkers (MCT-PD)
- Neuromodulation Effects of Deep Brain Stimulation on Beta Rhythm: A Longitudinal Local Field Potential Study.
- Modulation of the Microbiome in Parkinson’s Disease: Diet, Drug, Stool Transplant, and Beyond.
- Applications of Acupuncture Therapy in Modulating the Plasticity of Neurodegenerative Disease and Depression: Do MicroRNA and Neurotrophin BDNF Shed Light on the Underlying Mechanism?
- Molecular evolutionary and structural analysis of human UCHL1 gene demonstrates the relevant role of intragenic epistasis in Parkinson’s disease and other neurological disorders.
- The impact of cannabinoid type 2 receptors (CB2Rs) in neuroprotection against neurological disorders.
- [The role of the gut microbiome in idiopathic Parkinson’s disease].
- A novel wireless brain stimulation device for long-term use in freely moving mice.
- Study of UB-312 in Healthy Participants and Parkinson’s Disease Patients
- Utilization of the CRISPR-Cas9 Gene Editing System to Dissect Neuroinflammatory and Neuropharmacological Mechanisms in Parkinson’s Disease.
- Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism.
- The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease.
- OLE Study for Patients With Parkinson’s Disease With Dementia Enrolled in Study ANAVEX2-73-PDD-001
- Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
- Exploring celiac disease candidate pathways by global gene expression profiling and gene network cluster analysis.
- Parkinson’s Disease Isradipine Safety Study
- Factors That Influence Habitual Activity in Mild Cognitive Impairment and Dementia.
- Involvement of dopaminergic signaling in the cross talk between the renin-angiotensin system and inflammation.
- A Study to Evaluate the Effectiveness and Safety of LY03003 in Patients With Early Primary PD
- Treatment of Chronic Constipation in Parkinson’s Disease
- The application of iPSCs in Parkinson’s disease.
- Rho kinase inhibitor fasudil reduces L-DOPA-induced dyskinesia in a rat model of Parkinson´s disease.
- Quantitative Mapping of Substantia Nigra Iron in Parkinson’s Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls
- Artificial intelligence in celiac disease.
- Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy.
- Opioid Modulation of Neuronal Iron and Potential Contributions to NeuroHIV.
- Home Based Tele-exercise for People With Chronic Neurological Impairments: COVID and Beyond
- Gene therapy for neurodegenerative disorders: advances, insights and prospects.
- An automated microliter-scale high-throughput screening system (MSHTS) for real-time monitoring of protein aggregation using quantum-dot nanoprobes.
- The Role of Exosomes in Stemness and Neurodegenerative Diseases-Chemoresistant-Cancer Therapeutics and Phytochemicals.
- Gaps, Controversies, and Proposed Roadmap for Research in Normal Pressure Hydrocephalus.
- A Multiple Ascending Dose Study With LY03003 in Patients With Early-stage Parkinson’s Disease
- Surgical Treatment of Parkinson Disease.
- Discovery of a Series of Ester-substituted NLRP3 Inflammasome Inhibitors.
- Extracellular Vesicles as Nanotherapeutics for Parkinson’s Disease.
- Pro-cathepsin D, Prosaposin, and Progranulin: Lysosomal Networks in Parkinsonism.
- Parkin-linked Parkinson’s disease: From clinical insights to pathogenic mechanisms and novel therapeutic approaches.
- The Relation of the Brain-Derived Neurotrophic Factor with MicroRNAs in Neurodegenerative Diseases and Ischemic Stroke.
- An Open Label, Balanced, Randomised, 2-treatment, 2-period, 2-sequence, Single Oral Dose, Corssover Comparative PK Study of WD-1603 in Healthy Subjects Under Fasting Conditions
- Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity.
- VGLUT2 EXPRESSION IN DOPAMINE NEURONS CONTRIBUTES TO POST-LESIONAL STRIATAL REINNERVATION.
- Open-Label Safety Study of ADS-5102 in PD Patients With LID
- Feasibility and Acceptability of a Physical Activity Behavior Change Intervention for Parkinson’s Disease
- Treating Anxiety in Parkinson’s Disease With a Multi-Strain Probiotic
- Microglial inflammation and phagocytosis in Alzheimer’s disease: Potential therapeutic targets.
- Challenges and Opportunities of Deferoxamine Delivery for Treatment of Alzheimer’s Disease, Parkinson’s Disease, and Intracerebral Hemorrhage.
- A mitochondrial uncoupler prodrug protects dopaminergic neurons and improves functional outcome in a mouse model of Parkinson’s disease.
- An Increased Burden of Highly Active Retrotransposition Competent L1s Is Associated with Parkinson’s Disease Risk and Progression in the PPMI Cohort.
- Calcium imaging in freely-moving mice during electrical stimulation of deep brain structures.
- Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin.
- Phase 1/2a Clinical Trial of PR001A in Patients With Parkinson’s Disease With at Least One GBA1 Mutation (PROPEL)
- Does HIV infection contribute to increased beta-amyloid synthesis and plaque formation leading to neurodegeneration and Alzheimer’s disease?
- Noncoding RNAs and Midbrain DA Neurons: Novel Molecular Mechanisms and Therapeutic Targets in Health and Disease.
- Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans.
- Subthalamic Deep Brain Stimulation (DBS) in Parkinson’s Disease
- Resistant Maltodextrin for Gut Microbiome in Parkinson’s Disease: Safety and Tolerability Study
- Flexible-Dose, Adjunctive Therapy Trial in Adults With Parkinson’s Disease With Motor Fluctuations
- A Study of KW-6356 in Patients With Parkinson’s Disease on Treatment With Levodopa-containing Preparations
- The SUMO conjugase Ubc9 protects Dopaminergic cells from cytotoxicity and enhances the stability of α-synuclein in Parkinson’s disease models.
- A Novel Tri-culture Model for Neuroinflammation.
- Probiomimetics-Novel Lactobacillus-Mimicking Microparticles Show Anti-Inflammatory and Barrier-Protecting Effects in Gastrointestinal Models.
- A Novel Small Molecule Supports the Survival of Cultured Dopamine Neurons and May Restore the Dopaminergic Innervation of the Brain in the MPTP Mouse Model of Parkinson’s Disease.
- Inhibition of Retinoblastoma Cell Growth by CEP1347 Through Activation of the P53 Pathway.
- Varenicline for Gait and Balance Impairment in Parkinson Disease
- Discovery and Structure-Activity Relationships of Nociceptin Receptor Partial Agonists That Afford Symptom Ablation in Parkinson’s Disease Models.
- Safety and Efficacy of Pimavanserin in Adults With Parkinson’s Disease and Depression
- Machine learning discriminates a movement disorder in a zebrafish model of Parkinson’s disease.
- Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles.
- Tetramethylpyrazine ameliorates isoflurane-induced cognitive dysfunction by inhibiting neuroinflammation via miR-150 in rats.
- Current Management of Tics and Tourette Syndrome: Behavioral, Pharmacologic, and Surgical Treatments.
- Phase 2 Clinical Study of KW-6500 in Parkinson’s Disease Patients With Motor Response Complication on Levodopa Therapy
- Nanoparticle-Based Technology Approaches to the Management of Neurological Disorders.
- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches.
- State-dependent Pathophysiological Oscillations in Parkinson’s Disease and Treatment With Deep Brain Stimulation (DBS)
- Open Label, Safety, Tolerability and Efficacy of AFQ056 in Parkinson’s Patients With L-dopa Induced Dyskinesias
- Efficacy and Safety of AFQ056 When Combined With Increased Doses of L-dopa in Parkinson’s Disease Patients With Moderate-severe L-dopa Induced Dyskinesia
- Safety and Efficacy of AQW051 in L-dopa Induced Dyskinesias in Patients With Parkinson’s Disease
- Open-label, Long-term Safety Extension Study of AFQ056 in Parkinson’s Patients With L-dopa Induced Dyskinesias
- Determination of oxyphylla A enantiomers in the fruits of Alpinia oxyphylla by a chiral HPLC-MRM-MS method and comparison of their in vivo biological activities.
- Study to Evaluate the Effect of Lixisenatide in Patient With Parkinson’s Disease
- The role of resilience in irritable bowel syndrome, other chronic gastrointestinal conditions and the general population.
- Unique Novel role of Adropin in the gastric Ulcer in a rotenone-induced Rat model of Parkinson’s disease.
- Posiphen® Dose-Finding, Biomarker Study in Early Alzheimer’s and Parkinson’s Patients
- tDCS-Enhanced Consolidation of Writing Skills and Its Associations With Cortical Excitability in Parkinson Disease: A Pilot Study.
- Maternal bacteria to correct abnormal gut microbiota in babies born by C-section.
- Current Aspects of the Endocannabinoid System and Targeted THC and CBD Phytocannabinoids as Potential Therapeutics for Parkinson’s and Alzheimer’s Diseases: a Review.
- Ghrelin mitigates MPP+-induced cytotoxicity: involvement of ERK1/2-mediated Nrf2/HO-1 and endoplasmic reticulum stress PERK signaling pathway.
- Dopamine receptors in emesis: molecular mechanisms and potential therapeutic function.
- Angiotensin AT1 and AT2 receptor heteromer expression in the hemilesioned rat model of Parkinson’s disease that increases with levodopa-induced dyskinesia.
- Manganese Induced neurodegenerative diseases and possible therapeutic approaches.
- Transferrin1 modulates rotenone-induced Parkinson’s disease through affecting iron homeostasis in Drosophila melanogaster.
- Effectiveness of Botox on Reducing Rest Tremor in Parkinson’s Disease
- Key Mechanisms and Potential Targets of the NLRP3 Inflammasome in Neurodegenerative Diseases.
- WD-1603 PK Study Under Fasting and Fed Conditions in Healthy Subjects
- Gutting the brain of inflammation: A key role of gut microbiome in human umbilical cord blood plasma therapy in Parkinson’s disease model.
- An experience-based review of HIFU in functional interventional neuroradiology: transcranial MRgFUS thalamotomy for treatment of tremor.
- A Study That Compares the Extent to Which Apomorphine Becomes Available in the Body After Taking Either an Investigational Drug Containing Apomorphine or Apomorphine That is Injected Under the Skin in People With PD Complicated by “OFF” Episodes
- Therapeutic Potential for Intranasal Levodopa in Parkinson’s Disease -Off Reversal
- Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets.
- A Cardiac Safety Study of an Investigational Drug to See How if Affects the Heart in People With Parkinson’s Disease Complicated by Motor Fluctuations “OFF” Episodes
- Phase IIa Randomized Placebo Controlled Trial: Mesenchymal Stem Cells as a Disease-modifying Therapy for iPD
- Fecal microRNAs as Innovative Biomarkers of Intestinal Diseases and Effective Players in Host-Microbiome Interactions.
- Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Vasoactive Intestinal Peptide Against Cognitive Decline in Neurodegenerative Diseases.
- Progress in the molecular pathogenesis and nucleic acid therapeutics for Parkinson’s disease in the precision medicine era.
- Biofluid Markers for Prodromal Parkinson’s Disease: Evidence From a Catecholaminergic Perspective.
- A Study Evaluating Potential Screening Tools for Detecting Parkinson Disease
- Safety and Efficacy of Levetiracetam for the Management of Levodopa- Induced Dyskinesia in Patients with Parkinson’s Disease: A Systematic Review.
- Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Parkinson’s Disease
- Fecal Microbiota Transplantation As a Potential Treatment for Parkinson’s Disease
- Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism.
- Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration.
- Citalopram as a Posterior Cortical Protective Therapy in Parkinson Disease
- Image guidance in deep brain stimulation surgery to treat Parkinson’s disease: a comprehensive review.
- Status and future directions of clinical trials in Parkinson’s disease.
- Community-based genetic study of Parkinson´s disease in Estonia.
- Updated but not outdated “Gliadin”: A plant protein in advanced pharmaceutical nanotechnologies.
- Alleviating toxic α-Synuclein accumulation by membrane depolarization: evidence from an in vitro model of Parkinson’s disease.
- Data-driven evolution of neurosurgical gene therapy delivery in Parkinson’s disease.
- Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization.
- Levodopa Changes Functional Connectivity Patterns in Subregions of the Primary Motor Cortex in Patients With Parkinson’s Disease.
- Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation.
- CRISPR/Cas9 novel therapeutic road for the treatment of neurodegenerative diseases.
- Microglia and astrocyte dysfunction in parkinson’s disease.
- Amburana cearensis: Pharmacological and Neuroprotective Effects of Its Compounds.
- Integrative Analysis of Gene Expression and Regulatory Network Interaction Data Reveals the Protein Kinase C Family of Serine/Threonine Receptors as a Significant Druggable Target for Parkinson’s Disease.
- A Study to Examine APL-130277 in Patients With Parkinson’s Disease
- Efficacy, Safety and Tolerability Study of APL-130277 for the Acute Treatment of OFF Episodes in Patients With Parkinson’s Disease
- Autophagy-dependent removal of α-synuclein: a novel mechanism of GM1 ganglioside neuroprotection against Parkinson’s disease.
- The Role of Neurovascular System in Neurodegenerative Diseases.
- Dopaminergic Loss and Pain in Parkinson’s Disease
- Adrenergic Blockers for Cardiac Changes in Early Parkinson’s Disease
- Outcomes Mandate National Integration With Cannabis as Medicine
- Tocotrienols in Parkinson’s Disease (PD)
- Study of Urate Elevation in Parkinson’s Disease, Phase 3
- Reciprocal Upshot of Nitric Oxide, Endoplasmic Reticulum Stress, and Ubiquitin Proteasome System in Parkinson’s Disease Pathology.
- Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration.
- Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson’s disease: A case series.
- The class II histone deacetylases as therapeutic targets for Parkinson’s disease.
- Therapeutic Update on Huntington’s Disease: Symptomatic Treatments and Emerging Disease-Modifying Therapies.
- Identification of a Biomarker Predictive of Evolution of Parkinson Disease
- Natural Products as Modulators of Sirtuins.
- An update on the therapeutic potential of calpain inhibitors: a patent review.
- Transplantation of Neural Stem Cell-Derived Neurons for Parkinson’s Disease
- Phase 2b Follow-on Safety “Roll-over” Study
- Phytocannabinoids: General Aspects and Pharmacological Potential in Neurodegenerative Diseases.
- Demystifying autoimmune small bowel enteropathy.
- Chronic diarrhoea in adults: what not to miss.
- A Study to Evaluate ENT-01 for the Treatment of Parkinson’s Disease Dementia
- Gluten Degrading Enzymes for Treatment of Celiac Disease.
- Neuroprotective and neuro-survival properties of safinamide against methamphetamine-induced neurodegeneration: Hypothetic possible role of BDNF/TrkB/PGC-1α signaling pathway and mitochondrial uncoupling protein -2(UCP-2).
- Neuroepigenetics of arousal: Gamma oscillations in the pedunculopontine nucleus.
- Gene therapy, a novel therapeutic tool for neurological disorders: Current progress, challenges and future prospective.
- Neurorestorative Effects of a Novel Fas-Associated Factor 1 Inhibitor in the MPTP Model: An [18F]FE-PE2I Positron Emission Tomography Analysis Study.
- The purinergic P2X7 receptor as a potential drug target to combat neuroinflammation in neurodegenerative diseases.
- Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans.
- Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression
- A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Parkinson’s Disease Mild Cognitive Impairment (PD-MCI)
- Integrated Binary QSAR-Driven Virtual Screening and in vitro Studies for Finding Novel hMAO-B-Selective Inhibitors.
- G-protein coupled receptor 88 knockdown in the associative striatum reduces psychiatric symptoms in a translational male rat model of Parkinson disease.
- Rationally engineered prolyl endopeptidases from Sphingomonas capsulata with improved hydrolytic activity towards pathogenic peptides of celiac diseases.
- Tolerance to NeuroEPO in Parkinson Disease
- Multidisciplinary Study of Novel NMDA Modulation for Neurodegenerative Disorder
- Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: Finding ways for prevention.
- Does altering proteasomal activity and trafficking reduce the arborization mediated specific vulnerability of SNpc dopaminergic neurons of Parkinson’s disease?
- Elevated In Vitro Kinase Activity in Peripheral Blood Mononuclear Cells of Leucine-Rich Repeat Kinase 2 G2019S Carriers: A Novel Enzyme-Linked Immunosorbent Assay-Based Method.
- “The whole perimeter is difficult”: Parkinson’s disease and the conscious experience of walking in everyday environments.
- Epigenetic Basis of Lead-Induced Neurological Disorders.
- Modulation of GABA-A Receptors in Parkinson Disease-Flumazenil Arm
- Evaluation of Safety and Tolerability of Fetal Mesencephalic Dopamine Neuronal Precursor Cells for Parkinson’s Disease
- To Assess the Efficacy and Safety of Ceftriaxone in Patients With Mild to Moderate Parkinson’s Disease Dementia
- [Movement Disorders: What Are You Doing? What Can We Do?]
- FDOPA PET and Nutritional Support in Parkinson’s Disease
- New insights into cortico-basal-cerebellar connectome: clinical and physiological considerations.
- Nei-like 1 inhibition results in motor dysfunction and promotes inflammation in Parkinson’s disease mice model.
- GSK-3β inhibition by curcumin mitigates amyloidogenesis via TFEB activation and anti-oxidative Activity in human neuroblastoma cells.
- Transcranial magnetic stimulation and gait disturbances in Parkinson’s disease: A systematic review.
- Deciphering short stature in children.
- Role of Long Noncoding RNAs in Parkinson’s Disease: Putative Biomarkers and Therapeutic Targets.
- A Large-Scale Full GBA1 Gene Screening in Parkinson’s Disease in the Netherlands.
- Design and development of 1,3,5-triazine-thiadiazole hybrids as potent adenosine A2A receptor (A2AR) antagonist for benefit in Parkinson’s Disease.
- Successful treatment of clozapine-nonresponsive refractory hallucinations and delusions with pimavanserin, a serotonin 5HT-2A receptor inverse agonist.
- Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease.
- Complex Effects of Putative DRP-1 Inhibitors on Stress Responses in Mouse Heart and Rat Cardiomyoblasts.
- Improvement of lower urinary tract function by a selective serotonin 5-HT1A receptor agonist, NLX-112, after chronic spinal cord injury.
- A Single-dose Study to Investigate the Tolerance and Pharmacokinetics of Finamine Tablets in China
- A Clinical Study Trial of Phenlarmide in China
- Efficacy and Safety of Rotigotine in the Treatment of Patients With Early Stage of Primary Parkinson’s Disease
- A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function.
- Inhibition of α-synuclein Cell-cell Transmission by NMDAR Blocker, Memantine
- Human gene therapy approaches for the treatment of Parkinson’s disease: An overview of current and completed clinical trials.
- Transplantation of Stem Cells as a Potential Therapeutic Strategy in Neurodegenerative Disorders.
- Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease.
- Probiotics-prebiotic Fiber Therapy in Parkinson’s Disease Patients With Constipation
- Design and in vitro analysis of SIRT2 inhibitor targeting Parkinson’s disease.
- Pharmacokinetics and efficacy of a novel formulation of carbidopa-levodopa (Accordion Pill®) in Parkinson’s disease.
- Maackiain Ameliorates 6-Hydroxydopamine and SNCA Pathologies by Modulating the PINK1/Parkin Pathway in Models of Parkinson’s Disease in Caenorhabditis elegans and the SH-SY5Y Cell Line.
- Multiple Ascending Dose Study of MEDI1341 in Patients With Parkinson’s Disease
- Parkinson’s disease: etiopathogenesis and treatment.
- A novel pyrazolo [3,4-d] pyrimidine, KKC080106, activates the Nrf2 pathway and protects nigral dopaminergic neurons.
- Integrated robotics platform with haptic control differentiates subjects with Parkinson’s disease from controls and quantifies the motor effects of levodopa.
- Genomewide association study of Parkinson’s disease clinical biomarkers in 12 longitudinal patients’ cohorts.
- Ambroxol as a Treatment for Parkinson’s Disease Dementia
- Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress.
- Advancing gene therapies, methods, and technologies for Parkinson’s Disease and other neurological disorders.
- Pigment Epithelium-Derived Factor Affects Angiogenesis in Celiac Disease.
- Novel Strategies for Gene Therapy-Recent Advances in the Use of Exosomes for Disease Treatment.
- Adhesion Molecule L1 Agonist Mimetics Protect Against the Pesticide Paraquat-Induced Locomotor Deficits and Biochemical Alterations in Zebrafish.
- Proteomic profiling of striatal tissue of a rat model of Parkinson’s disease after implantation of collagen-encapsulated human umbilical cord mesenchymal stem cells.
- A Clinical Study of Mesdopetam in Patients With Parkinson’s Disease Experiencing Levodopa Induced Dyskinesia
- Does outpatient palliative care improve patient-centered outcomes in Parkinson’s disease: Rationale, design, and implementation of a pragmatic comparative effectiveness trial.
- Open Label Continuation Treatment Study With Levodopa-Carbidopa Intestinal Gel in Advanced PD
- A Pilot Clinical Trial With the Iron Chelator Deferiprone in Parkinson’s Disease
- Nasal Resistance (NR) Technique: A Novel Approach to Improve Glottal Adduction.
- “LRRK2: Autophagy and Lysosomal Activity”.
- High Frequency Oscillations in Neurologic Disease
- EIn vivo modeling of prodromal stage of Parkinson’s disease.
- Clinical utility of SUDOSCAN in predicting autonomic neuropathy in patients with Parkinson’s disease.
- Chronic Effects of DBS in Parkinson’s Disease and Dystonia
- Stereotactic Transplantation of hAESCs for Parkinson’s Disease
- Oxyphylla A Promotes Degradation of α-Synuclein for Neuroprotection via Activation of Immunoproteasome.
- Evidence-Based Evaluation of the Ethics of Sham Surgery for Parkinson’s Disease.
- Prevalence of Dyskinesia and OFF by 30-Minute Intervals Through the Day and Assessment of Daily Episodes of Dyskinesia and OFF: Novel Analyses of Diary Data from Gocovri Pivotal Trials.
- Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility.
- MiR-302b-5p enhances the neuroprotective effect of IGF-1 in methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s disease by regulating inducible nitric-oxide synthase.
- Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson’s disease.
- Degradation of Tyrosine Hydroxylase by the Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease and Dopa-Responsive Dystonia.
- Detecting Common Pathways and Key Molecules of Neurodegenerative Diseases from the Topology of Molecular Networks.
- Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson’s disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study.
- Multifaceted targeting of neurodegeneration with bioactive molecules of saffron (Crocus sativus): An insilco evidence-based hypothesis.
- A thin-film multichannel electrode for muscle recording and stimulation in neuroprosthetics applications.
- Cholinergic Mechanisms of Gait Dysfunction in Parkinson’s Disease Exp. 3 – Proj#3 (UdallP3)
- The preclinical discovery and development of opicapone for the treatment of Parkinson’s disease.
- Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective.
- Induced pluripotent stem cells (iPSCs) as game-changing tools in the treatment of neurodegenerative disease: Mirage or reality?
- Intranasal delivery of mucoadhesive nanocarriers: a viable option for Parkinson’s disease treatment?
- Salidroside ameliorates Parkinson’s disease by inhibiting NLRP3-dependent pyroptosis.
- Mitophagy in Parkinson’s Disease: from pathogenesis to treatment target.
- Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD)
- Safety and Biomarker Study of EPI-589 in Parkinson’s Disease
- Combining data integration and molecular dynamics for target identification in α-Synuclein-aggregating neurodegenerative diseases: Structural insights on Synaptojanin-1 (Synj1).
- Gold nanoclusters for Parkinson’s disease treatment.
- Novel Treatment Opportunities Against Cognitive Impairment in Parkinson’s Disease with an Emphasis on Diabetes-Related Pathways.
- Wearable Ultrasound Improves Motor Function in an MPTP Mouse Model of Parkinson’s Disease.
- Immediate effects of rhythmic auditory stimulation on gait kinematics in Parkinson’s disease ON/OFF medication.
- Cholinergic Mechanisms of Gait Dysfunction in Parkinson’s Disease – Proj#3
- Invasive and Noninvasive Brain Stimulation in Parkinson’s Disease: Clinical Effects and Future Perspectives.
- Utilization Patterns of Amantadine in Parkinson’s Disease Patients Enrolled in the French COPARK Study.
- Potential Role of Vitamin D in the Elderly to Resist COVID-19 and to Slow Progression of Parkinson’s Disease.
- Terazosin Effect on Cardiac Changes in Early Parkinson’s Disease
- Development of a novel method for the quantification of tyrosine 39 phosphorylated α- and β-synuclein in human cerebrospinal fluid.
- A Study of Efficacy and Safety of Idebenone vs. Placebo in Prodromal Parkinson Disease
- A Randomized, Open-Label, Crossover Study to Evaluate the Pharmacokinetic Profiles of Rotigotine After a Single Dose of LY03003 (28 mg) Versus After a Week of Daily NEUPRO® Transdermal Patch (4 mg Every 24 Hours) in Healthy Volunteers
- Enhancement of ATP production ameliorates motor and cognitive impairments in a mouse model of MPTP-induced Parkinson’s disease.
- A simulated environment for early development stages of reinforcement learning algorithms for closed-loop deep brain stimulation.
- Modulation of GABA-A Receptors in Parkinson Disease-Transdermal Flumazenil Arm
- Improving Walking Automaticity in Parkinson’s Disease: Levodopa or Donepezil
- Safety and Efficacy of Liraglutide in Parkinson’s Disease
- Study Comparing Continuous Subcutaneous Infusion Of ABBV-951 With Oral Carbidopa/Levodopa Tablets For Treatment Of Motor Fluctuations In Adult Participants With Advanced Parkinson’s Disease
- PLA2 G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment.
- Extension Study To Evaluate Safety And Tolerability Of 24-Hour Daily Exposure Of Continuous Subcutaneous Infusion of ABBV-951 In Adult Participants With Parkinson’s Disease
- Study in Parkinson’s Disease Patients With Dyskinesia With Combinations of JM-010 and Its Individual Components (SHINE)
- Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson’s Disease: A New Therapeutic Strategy.
- “Sick-but-not-dead”: Multiple paths to catecholamine deficiency in Lewy Body diseases.
- Four main therapeutic keys for Parkinson’s disease: A mini review.
- A novel alpha-lipoic acid-3-n-butylphthalide conjugate enhances protective effects against oxidative stress and 6-OHDA induced neuronal damage.
- PET Evaluation of Microglial Activation in Non-neurodegenerative Brain Diseases.
- Neuroimaging Technological Advancements for Targeting in Functional Neurosurgery.
- Chronic 2-Fold Elevation of Endogenous GDNF Levels Is Safe and Enhances Motor and Dopaminergic Function in Aged Mice.
- A Clinical Study in Advanced Parkinson’s Disease Investigating the Long Term Safety of ND0612 Administered as a Continuous SC Infusion
- Two-weeks treatment with cannabidiol improves biophysical and behavioral deficits associated with experimental type-1 diabetes.
- Novel Insights into PARK7 (DJ-1), a Potential Anti-Cancer Therapeutic Target, and Implications for Cancer Progression.
- A Two-Stage Tremor Detection Algorithm for Wearable Inertial Sensors During Normal Daily Activities.
- Study Assessing Efficacy and Safety of AKST4290 in Subjects With Parkinson’s Disease on Stable Dopaminergic Treatment
- The Dichotomic Role of Macrophage Migration Inhibitory Factor in Neurodegeneration.
- Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria.
- A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone.
- Pain-Induced Beta Activity in the Subthalamic Nucleus of Parkinson’s Disease.
- Clonazepam improves the symptoms of two siblings with novel variants in the SYNJ1 gene.
- Walking to Music and Metronome at Various Tempi in Persons With Multiple Sclerosis: A Basis for Rehabilitation.
- Identification of biomarkers associated with Parkinson’s disease by gene expression profiling studies and bioinformatics analysis.
- Study Evaluating Intepirdine (RVT-101) on Gait and Balance in Subjects With Dementia
- The Messenger Apps of the cell: Extracellular Vesicles as Regulatory Messengers of Microglial Function in the CNS.
- Brain impedance variation of directional leads implanted in subthalamic nuclei of Parkinsonian patients.
- Freezing of gait in Parkinson’s disease: pathophysiology, risk factors and treatments.
- Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders.
- Relapse Prevention Study of Pimavanserin in Dementia-related Psychosis
- Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study.
- Mitochondrial Dysfunction and Parkinson’s Disease-Near-Infrared Photobiomodulation as a Potential Therapeutic Strategy.
- Pain in Parkinson’s disease: new concepts in pathogenesis and treatment.
- Discovery of Novel Compounds Targeting DJ-1 as Neuroprotectants for Parkinson’s Disease by Virtual Screening and in Silico Method.
- Early Expression of Neuronal Dopaminergic Markers in a Parkinson’s Disease Model in Rats Implanted with Enteric Stem Cells (ENSCs).
- Caring Interactions in Secondary Prevention Programs: A Qualitative Inquiry of Individuals With Parkinson’s Disease.
- Role of flavonoids in neurodegenerative diseases: Limitations and future perspectives.
- Structural and Functional Evidence for Citicoline Binding and Modulation of 20S Proteasome Activity: Novel Insights into its Pro-Proteostatic Effect.
- GDNF Promotes Survival and Therapeutic Efficacy of Human Adipose-Derived Mesenchymal Stem Cells in a Mouse Model of Parkinson’s Disease.
- Ambroxol in Disease Modification in Parkinson Disease
- Evaluation of [18F]MNI-1126 as an Imaging Marker for Synaptic Density Loss
- Study of OXB-102 (AXO-Lenti-PD) in Patients With Bilateral, Idiopathic Parkinson’s Disease
- The Role of the Noradrenergic System in the Nonmotor Symptoms of Parkinson’s Disease
- Lipid-based nanoformulations in the treatment of neurological disorders.
- A preliminary study of Parkinson’s gene therapy via sono-magnetic sensing gene vector for conquering extra/intracellular barriers in mice.
- Effects of Transcranial Direct Current Stimulation on Postural Control
- Phase I, KM-819 in Healthy Subjects for Parkinson’s Disease
- A Through QT/QTc Study of KW-6356
- Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements.
- Positive allosteric modulators of the dopamine D1 receptor: A new mechanism for the treatment of neuropsychiatric disorders.
- Study of Clonidine Efficacy for the Treatment of Impulse Control Disorders in Parkinson’s Disease:
- The Relationship Between Neuropsychological Testing and MRI, PET and COBRE – Project 1: AIM 2 (GE-180)
- PK Study in Patients With Parkinson’s Disease With IZD174
- Rapid Eye Movement Sleep Behavior Disorder and Neurodegenerative Diseases: An Update.
- ORALLY ADMINISTERED NANOTHERAPEUTICS FOR PARKINSON DISEASE: AN OLD DELIVERY SYSTEM YET MORE ACCEPTABLE.
- Effect of TAK-071 on Falls in Patients With Parkinson Disease
- The gut microbiome in Parkinson’s disease: A culprit or a bystander?
- Mechanisms of alpha-synuclein toxicity: An update and outlook.
- Combined mGlu2 orthosteric stimulation and positive allosteric modulation alleviates L-DOPA-induced psychosis-like behaviours and dyskinesia in the parkinsonian marmoset.
- Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson’s disease via suppressions of CRMP2 phosphorylation and microglial activation.
- Bio Electro Stimulation Therapy for Parkinson’s Disease
- Study Comparing Intravenous and Subcutaneous Infudopa With Intestinal Duodopa in Patients With Parkinson’s Disease